Chemical Genomics Instrumentation

Liquid Handling

The Multidrop is a simple- to-use liquid dispenser for 96- and 384-well plates. In the tissue culture hood, it performs sterile transfers of suspended cells and media to screening plates for cell-based assays.

The Aquarius is the main screening liquid handler. It can transfer reagents from reservoirs or deep 96-well plates into stacks of 384 well assay plates using disposable tips. Compound transfers using steel pins are performed here. It can also be used to create 384-well plates from 96-well stocks.
The EVO has fixed- tips, ideal for serial dilutions, dose-response or creating plates from samples in Eppendorf tubes. A robotic arm can move plates around the deck and to components such as the plate washer, plate shaker, incubator and plate reader.
Plate Reading
The Envision plate reader is a filter-based instrument that can quantify signals from colorimetric, fluorescent intensity, fluorescent polarization, FRET, time-resolved fluorescent and luminescent assays. It is extremely sensitive and therefore ideal for reading 384-well plates with assay volumes ~20 uL. Check available filters here.

Janie Merkel, Ph.D., Director
Yale University, 219 Prospect St, KBT 700, New Haven, CT 06511
janie.merkel@yale.edu, 203-432-5930