Resources

The CGP has facilities and equipment to support the research, teaching and training missions for each of the four Cores. These are located at various sites on the Yale campus and most are shared by all the Cores and other researchers at Yale.

North Campus

The prime teaching, training and seminar activities of CGP take place in the laboratories and classrooms of the Department of Molecular Cellular and Developmental Biology (MCDB) (Kline Biology Tower, Osborn Memorial Laboratories), the Department of Molecular Biophysics and Biochemistry (MB&B) (Bass Center and Gibbs Research Laboratory) and the Department of Ecology and Environmental Biology (Environmental Science Center).

Many of the Functional Genomics and Proteomics resources are located on Science Hill in these buildings. KBT houses equipment for high throughput DNA and protein production, liquid handling systems, 2 arrayers including a Virtex contact printer, scanners. A new LC MS/MS spec will be added. Most of the plant molecular and genomics facilities are in OML including growth chambers, microscopes with digital optics including a laser capture microscope and other equipment to support microarray research and bioinformatics for sample tracking and analysis. A high throughput sequencing facility is located in ESC. The Chemical Genomics Core facility is currently being set up in KBT and will have a small molecule screening core for molecular and cell based assays.

The Bioinformatics Core has components on the North, Central and South Campus areas. Bass and Gibbs, on the North campus, house the genomics-computing laboratory. It houses desktop computers, servers, and shared resources that are interconnected using gigabit Ethernet technologies, which provide a high-speed infrastructure for them. CGP is also associated with the Core computing laboratory of the Yale Center for Structural Biology and these resources are used by CGP.

Mid Campus

The Department of Computer Science (Arthur K. Watson Hall) has a very large cluster of computers that are available to CGP researchers and are used by Computer Science and Engineering for a variety of projects in high performance computing.

South Campus

Most activities of the Medical Genomics Core and many of the Bioinformatics Core (through the association with the Yale Center for Medical Informatics (YCMI) take place in and around the Yale School of Medicine and associated buildings and facilities. Medical Genomics will have a high throughput genotyping facility, a Cellzome Cell Screening facility and liquid handling facilities. Through YCMI, CGP personnel have access to an assortment of desktop PC and Macintosh machines and the YCMI currently maintains or has access to several database management servers.

The Keck Foundation Biotechnology Resource Laboratory (KFBRL) and the associated Yale NIHLB Center of Proteomics provide a valuable resource for CGP and indeed the whole Yale community. It is a center of service and research for a wide range of genomic and proteomic biotechnologies.Genomics and proteomic syntheses include DNA microarray and chip technology, oligo and peptide synthesis, DNA and protein sequencing, biophysical analysis of proteins and other biopolymers, biostatistical analyses, and mass spectrometry (MS). The Functional Genomic and Proteomics Micromass Q-TOF is housed in the Keck Center.